Dr Jude Oben

Consultant Gastroenterologist/Hepatologist and Obesity Physician

BM,BCh (Oxon), Ph.D, FRCP (Lond & Edin)

Year qualified:1994


Personal profile

Dr Jude A Oben - a clinician scientist - holds consultant appointments in gastroenterology and hepatology at Guy’s & St Thomas’ Hospital, and in Hepatology at the Royal Free Hospital, London. 

He is also a senior lecturer in hepatology at University College London, Institute for Liver and Digestive Health. Dr Oben has a Ph.D in immuno-pharmacology from UCL and studied medicine at Oxford, with a stint at Stanford University, Palo Alto, USA, as a research fellow in Immunology. After Oxford, initial post-graduate medical training was at the Hammersmith hospital. During his specialist registrar training he re-orientated his research career with some 2 years as a post-doctoral fellow at Johns Hopkins University, Baltimore, USA, under the mentorship of Professor Anna Mae Diehl. 

Dr Oben’s work at Johns Hopkins combined his previous interest in neuroscience with liver medicine and he discovered that the autonomic nervous system regulates liver repair through actions on liver stem cells and liver stellate cells, in the context of obesity induced liver disease. On the back of a very productive period at Johns Hopkins he was awarded a Welcome Trust Fellowship funding stream on returning to London. 

He leads a productive research group at the UCL Institute for Liver and Digestive Health, Royal Free Hospital and continues to juggle clinical and basic science research with clinical practice in gastroenterology and hepatology. His research focuses on obesity induced liver disease (non-alcoholic fatty liver disease), liver regeneration and mechanism of fibrosis in Crohn’s disease.  

Dr Oben is a co-founder and Trustee of the Obesity Action Campaign recently launched at the House of Lords: the primary aim being to raise political and public awareness of obesity and its deleterious health consequences especially in adolescents. He is an invited member of the All Party Parliamentary Group on Obesity. As a key opinion leader in Obesity and Fatty liver disease he is regularly interviewed by the media - print and television.

Professional Memberships

  • American Association for the Study of Liver Diseases
  • American Gastroenterological Association
  • American Society for Gastrointestinal Endoscopy
  • British Society of Gastroenterology
  • British Association for the Study of the Liver 
  • European Association for the Study of the Liver
  • The Obesity Society
  • Royal College of Physicians (London)
  • Royal College of Physicians (Edinburgh)
  • Royal Society of Medicine (UK)

Clinical Interests

  • General gastroenterology and hepatology
  • Based on ongoing laboratory research experience - fatty liver disease associated with obesity, type 2 diabetes, hypertension and cardiovascular disease
  • Endoscopic treatment of obesity

Special clinical interests:

  • All aspects of gastroenterology and hepatology (liver medicine), therapeutic and diagnostic endoscopy, obesity - medical and endoscopic management via intra-gastric balloons

Current NHS and /or University Posts

  • Guy's and St Thomas'Hospital
  • Royal Free Hospital

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