Dr McAlindon trained in Nottingham, Stoke-on-Trent and Melbourne, Australia. He was awarded a British Digestive Foundation Training Fellowship in 1994, researching mechanisms of inflammation in Crohn's disease and colitis and also received a PhD.
Since being appointed as a consultant in Sheffield in 1998, he has led endoscopy and nutrition services and developed capsule endoscopy. He is active in research in these areas, has published original research papers and reviews and lectures nationally and internally on capsule endoscopy. The Sheffield Small Bowel Endoscopy service was recently a runner-up in the National Health Services Journal Award for patient safety. He chairs the gastrostomy group which was awarded first place in the integrated care category of the same national award.