Dr Sharon O'Brien

Consultant Gastroenterologist

MD, FRCP

Personal profile

Dr O’Brien was appointed as a Consultant Gastroenterologist and General Physician at Central Middlesex Hospital in 1999. She trained at St Vincent’s University Hospital in Dublin and completed her specialist training at The Middlesex and Central Middlesex Hospitals in London. Her major research interest was in the field of cholestatic liver disease. This was the subject of many publications and her M.D. thesis. She has also published research on portal haemodynamics in patients with chronic liver disease, the use of metal stents in the management of benign and malignant biliary obstruction and the identification of TPMT polymorphisms in the prediction of myelosuppression in patients taking azathioprine. She has presented her research at national and international scientific meetings.

In her NHS practice Dr O’Brien has managed patients with a wide spectrum of gastrointestinal, liver, pancreatic and biliary disorders as well as working as a general physician. Until 2018 she was the lead physician for IBD at Central Middlesex Hospital, running a dedicated clinic for patients with ulcerative colitis and Crohn’s disease. Dr O’Brien is committed to providing the highest standards of patient care and communication. Over the years she has had excellent results from patient satisfaction surveys and countless complimentary letters from patients. As a female gastroenterologist at the Clementine Churchill Hospital, Dr O’Brien is pleased to provide a service for women with gastrointestinal problems.

To make an appointment to see Dr O’Brien please obtain a referral letter from your G.P. and phone the booking centre at The Clementine Churchill Hospital (020 8872 3838) to arrange. Please note that Dr O’Brien does not perform endoscopic procedures.

Professional Memberships

  • British Society of Gastroenterology
  • British Association for the Study of the Liver
  • British Medical Association
  • General Medical Council
  • Medical Defence Union

Clinical Interests



  • All aspects of medical gastroenterology

  • Cholestatic and alcohol related liver disease

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