Dr Karp trained in Clinical Oncology at the Middlesex and Mount Vernon Hospitals.
Dr Karp was appointed a Consultant in 1990. Initially practising in a wide range of tumour types he now specialises in treating cancers of the breast, GI tract (colo-rectal, oesophago-gastric, pancreatic) and urological cancer (prostate and bladder cancer) with chemotherapy, hormonal therapy, biological therapy and radiotherapy.
Dr Karp led the Royal College of Radiologists COIN project which produced 6 national cancer guidelines including breast and prostate cancer. Dr Karp also specialises in using radiotherapy treatments including Cyberknife, IMRT, IGRT and adaptive radiotherapy.
Dr Karp also carries out medico-legal work related to cancer.